Not only its sum and also the purposeful properties of Hb have an affect on effectiveness. This is often illustrated with the observation that an increased Hb-O2 affinity favors O2 loading during the lung and survival in an hypoxic surroundings (Eaton et al., 1974; Hebbel et al., 1978), whereas a reduced Hb-O2 affinity favors the release of O2 with
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